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1

Long-term administration of pDC-Stimulative Lactococcus lactis strain decelerates senescence and prolongs the lifespan of mice

Sugimura, Tetsu, Jounai, Kenta, Ohshio, Konomi, Suzuki, Hiroaki, Kirisako, Takayoshi, Sugihara, Yoshihiko, Fujiwara, Daisuke

Journal:

International Immunopharmacology

Year:

2018

Language:

english

File:

PDF, 548 KB

english, 2018

2

Administration of plasmacytoid dendritic cell-stimulative lactic acid bacteria enhances antigen-specific immune responses

Suzuki, Hiroaki, Jounai, Kenta, Ohshio, Konomi, Fujii, Toshio, Fujiwara, Daisuke

Journal:

Biochemical and Biophysical Research Communications

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

3

Uniaxial drawing of polytetrafluoroethylene virgin powder by extrusion plus cold tensile draw

Ryoukei Endo, Kazuhiro Jounai, Hiroki Uehara, Tetsuo Kanamoto, Roger S. Porter

Journal:

Journal of Polymer Science Part B: Polymer Physics

Year:

1998

Language:

english

File:

PDF, 337 KB

english, 1998

4

A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV

Ke-Qin Xin, Takaaki Ooki, Nao Jounai, Hiroaki Mizukami, Kenji Hamajima, Yoshitsugu Kojima, Kenji Ohba, Yoshihiko Toda, Syu-Ichi Hirai, Dennis M. Klinman, Keiya Ozawa, Dr Kenji Okuda

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

5

Contribution of the rev gene to the immunogenicity of DNA vaccines targeting the envelope glycoprotein of HIV

Nao Jounai, Kenji Okuda, Yoshitsugu Kojima, Yoshihiko Toda, Kenji Hamajima, Kenji Ohba, Dennis Klinman, Dr Ke-Qin Xin

Journal:

The Journal of Gene Medicine

Year:

2003

Language:

english

File:

PDF, 228 KB

english, 2003

6

Efficient algorithms for computing the characteristic polynomial in a domain

Jounaı̈di Abdeljaoued, Gennadi I. Malaschonok

Journal:

Journal of Pure and Applied Algebra

Year:

2001

Language:

english

File:

PDF, 131 KB

english, 2001

7

Detection of a CYP3A5 Allelic Variant: A Candidate for the Polymorphic Expression of the Protein?

Y. Jounaı&amp, #x0308, di, Valérie Hyrailles, Laurence Gervot, Patrick Maurel

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 160 KB

english, 1996

8

Polygene DNA vaccine induces a high level of protective effect against HIV-vaccinia virus challenge in mice

Kaori Shinoda, Ke-Qin Xin, Nao Jounai, Yoshitsugu Kojima, Yuichi Tamura, Eiichi Okada, Susumu Kawamoto, Katsuji Okuda, Dennis Klinman, Kenji Okuda

Journal:

Year:

2004

Language:

english

File:

PDF, 600 KB

english, 2004

9

Comparison of antigen-specific cellular immune responses between individual PBMCs and splenocytes

Ke-Qin Xin, Shinrai Ohta, Nao Jounai, Fumihiko Takeshita, Kenji Okuda

Journal:

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

10

Oral administration of the adenovirus vector induces systemic immunity rather than intestinal mucosal immunity

Kenji Oomura, Ke-Qin Xin, Momoko Takakura, Kaori Shinoda, Nao Jounai, Kenji Okuda

Journal:

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

11

The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection

Yoshitsugu Kojima, Nao Jounai, Fumihiko Takeshita, Masatoshi Nakazawa, Kentaro Okuda, Setsuko Watabe, Ke-Qin Xin, Kenji Okuda

Journal:

Year:

2007

Language:

english

File:

PDF, 698 KB

english, 2007

12

DNA vaccine expressing HIV-1 gp120/immunoglobulin fusion protein enhances cellular immunity

Masaru Shimada, Shinji Yoshizaki, Nao Jounai, Asami Kondo, Motohide Ichino, Akihide Ryo, Kenji Okuda

Journal:

Year:

2010

Language:

english

File:

PDF, 489 KB

english, 2010

13

Adjuvant effect of multi-CpG motifs on an HIV-1 DNA vaccine

Yoshitsugu Kojima, Ke-Qin Xin, Takaaki Ooki, Kenji Hamajima, Tomohiro Oikawa, Kaori Shinoda, Tomomi Ozaki, Yuka Hoshino, Nao Jounai, Masatoshi Nakazawa, Dennis Klinman, Kenji Okuda

Journal:

Year:

2002

Language:

english

File:

PDF, 450 KB

english, 2002

14

Recombinant vaccinia virus (WR strain) may not be suitable for ex vivo stimulation

Ke-Qin Xin, Yasuko Kumamoto, Nao Jounai, Yoshitsugu Kojima, Kenji Hamajima, Kenji Okuda

Journal:

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

15

Human Immunodeficiency Virus in Uzbekistan: Epidemiological and Genetic Analyses

Kurbanov, Fuat, Kondo, Makiko, Tanaka, Yasuhito, Zalalieva, Mariam, Giasova, Guzal, Shima, Takako, Jounai, Nao, Yuldasheva, Nadira, Ruzibakiev, Ruslan, Mizokami, Masashi, Imai, Mitsunobu

Journal:

AIDS Research and Human Retroviruses

Year:

2003

Language:

english

File:

PDF, 252 KB

english, 2003

16

Detection of progeny immune responses after intravenous administration of DNA vaccine to pregnant mice

Ke-Qin Xin, Shin Sasaki, Yoshitsugu Kojima, Nao Jounai, Yasuko Kumamoto, Kumiko Hashimoto, Kaori Shinoda, Kenji Hamajima, Kenji Okuda

Journal:

Biological Procedures Online

Year:

2001

Language:

english

File:

PDF, 429 KB

english, 2001

17

Innate Immune Signaling by, Genetic Adjuvants for, DNA Vaccination

Kobiyama, Kouji, Jounai, Nao, Aoshi, Taiki, Tozuka, Miyuki, Takeshita, Fumihiko, Coban, Cevayir, Ishii, Ken

Journal:

Year:

2013

Language:

english

File:

PDF, 685 KB

english, 2013

18

Immunomodulatory effect of Lactococcus lactis JCM5805 on human plasmacytoid dendritic cells

Sugimura, Tetsu, Jounai, Kenta, Ohshio, Konomi, Tanaka, Takaaki, Suwa, Masahiro, Fujiwara, Daisuke

Journal:

Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

19

Oral Administration of Recombinant Adeno-Associated Virus Elicits Human Immunodeficiency Virus-Specific Immune Responses

Xin, Ke-Qin, Ooki, Takaaki, Mizukami, Hiroaki, Hamajima, Kenji, Okudela, Koji, Hashimoto, Kumiko, Kojima, Yoshitsugu, Jounai, Nao, Kumamoto, Yasuko, Sasaki, Shin, Klinman, Dennis, Ozawa, Keiya, Okuda,

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 398 KB

english, 2002

20

Chitin Micro-Particles (CMP): A Useful Adjuvant for Inducing Viral Specific Immunity when Delivered Intranasally with an HIV-DNA Vaccine

Hamajima, Kenji, Kojima, Yoshizumi, Matsui, Kiyohiko, Toda, Yoshihiko, Jounai, Nao, Ozaki, Tomomi, Xin, Ke-Qin, Strong, Peter, Okuda, Kenji

Journal:

Viral Immunology

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

21

The Atg5 Atg12 conjugate associates with innate antiviral immune responses

Jounai, N., Takeshita, F., Kobiyama, K., Sawano, A., Miyawaki, A., Xin, K.-Q., Ishii, K. J., Kawai, T., Akira, S., Suzuki, K., Okuda, K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 792 KB

english, 2007

22

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN

Temizoz, Burcu, Kuroda, Etsushi, Ohata, Keiichi, Jounai, Nao, Ozasa, Koji, Kobiyama, Kouji, Aoshi, Taiki, Ishii, Ken J.

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 792 KB

english, 2015

23

Blocking of the TLR5 Activation Domain Hampers Protective Potential of Flagellin DNA Vaccine

Saha, S., Takeshita, F., Matsuda, T., Jounai, N., Kobiyama, K., Matsumoto, T., Sasaki, S., Yoshida, A., Xin, K.-Q., Klinman, D. M., Uematsu, S., Ishii, K. J., Akira, S., Okuda, K.

Journal:

The Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

24

DNA vaccines

Coban, Cevayir, Kobiyama, Kouji, Jounai, Nao, Tozuka, Miyuki, Ishii, Ken J

Journal:

Human Vaccines & Immunotherapeutics

Year:

2013

Language:

english

File:

PDF, 299 KB

english, 2013

25

NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1

Jounai, N., Kobiyama, K., Shiina, M., Ogata, K., Ishii, K. J., Takeshita, F.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

26

Extrachromosomal Histone H2B Mediates Innate Antiviral Immune Responses Induced by Intracellular Double-Stranded DNA

Kobiyama, K., Takeshita, F., Jounai, N., Sakaue-Sawano, A., Miyawaki, A., Ishii, K. J., Kawai, T., Sasaki, S., Hirano, H., Ishii, N., Okuda, K., Suzuki, K.

Journal:

Journal of Virology

Year:

2010

Language:

english

File:

PDF, 2.10 MB

english, 2010

27

Application of Innate Immune Molecules for a New Class of Drugs: Infection, Inflammation and Beyond

J. Kimura, H., Suzuki, K., A. Landek-Salgado, M., Caturegli, P., Jounai, N., Kobiyama, K., Takeshita, F.

Journal:

Endocrine Metabolic & Immune Disorders - Drug Targets

Year:

2011

Language:

english

File:

PDF, 187 KB

english, 2011

28

The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling

Takeshita, Fumihiko, Kobiyama, Kouji, Miyawaki, Atsushi, Jounai, Nao, Okuda, Kenji

Journal:

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

29

Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV

Xin, K-Q, Jounai, N, Someya, K, Honma, K, Mizuguchi, H, Naganawa, S, Kitamura, K, Hayakawa, T, Saha, S, Takeshita, F, Okuda, K, Honda, M, Klinman, D M, Okuda, K

Journal:

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

30

Efficient antigen delivery to the draining lymph nodes is a key component in the immunogenic pathway of the intradermal vaccine

Tozuka, Miyuki, Oka, Tatsuya, Jounai, Nao, Egawa, Gyohei, Ishii, Ken J., Kabashima, Kenji, Takeshita, Fumihiko

Journal:

Journal of Dermatological Science

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

31

High Modulus Films of Polytetrafluoroethylene Prepared by Two-Stage Drawing of Reactor Powder

Uehara, Hiroki, Jounai, Kazuhiro, Endo, Ryoukei, Okuyama, Hiroshi, Kanamoto, Tetsuo, Porter, Roger S

Journal:

Polymer Journal

Year:

1997

File:

PDF, 566 KB

1997

32

Effects of oral intake of plasmacytoid dendritic cells-stimulative lactic acid bacterial strain on pathogenesis of influenza-like illness and immunological response to influenza virus

Sugimura, Tetsu, Takahashi, Hitoshi, Jounai, Kenta, Ohshio, Konomi, Kanayama, Masaya, Tazumi, Kyoko, Tanihata, Yoko, Miura, Yutaka, Fujiwara, Daisuke, Yamamoto, Norio

Journal:

British Journal Of Nutrition

Year:

2015

Language:

english

File:

PDF, 728 KB

english, 2015

33

Erratum to “Immunomodulatory effect of Lactococcus lactis JCM5805 on human plasmacytoid dendritic cells” [Clin. Immunol. 149 (2013) 509-518]

Sugimura, Tetsu, Jounai, Kenta, Ohshio, Konomi, Tanaka, Takaaki, Suwa, Masahiro, Fujiwara, Daisuke

Journal:

Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 116 KB

english, 2015

34

Ligand-induced Ordering of the C-terminal Tail Primes STING for Phosphorylation by TBK1

Tsuchiya, Yuko, Jounai, Nao, Takeshita, Fumihiko, Ishii, Ken J., Mizuguchi, Kenji

Journal:

Year:

2016

Language:

english

File:

PDF, 2.99 MB

english, 2016

35

Age-Specific Profiles of Antibody Responses against Respiratory Syncytial Virus Infection

Jounai, Nao, Yoshioka, Megumi, Tozuka, Miyuki, Inoue, Kazue, Oka, Tatsuya, Miyaji, Kazuki, Ishida, Katsuyasu, Kawai, Naoki, Ikematsu, Hideyuki, Kawakami, Chiaki, Shimizu, Hiroyuki, Mori, Masaaki, Ishi

Journal:

Year:

2017

Language:

english

File:

PDF, 2.12 MB

english, 2017

36

CD63-Mediated Antigen Delivery into Extracellular Vesicles via DNA Vaccination Results in Robust CD8 + T Cell Responses

Kanuma, Tomohiro, Yamamoto, Takuya, Kobiyama, Kouji, Moriishi, Eiko, Masuta, Yuji, Kusakabe, Takato, Ozasa, Koji, Kuroda, Etsushi, Jounai, Nao, Ishii, Ken J.

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

37

Effects of heat-killed Lactococcus lactis subsp. lactis JCM 5805 on mucosal and systemic immune parameters, and antiviral reactions to influenza virus in healthy adults; a randomized controlled double-blind study

Fujii, Toshio, Jounai, Kenta, Horie, Akira, Takahashi, Hitoshi, Suzuki, Hiroaki, Ohshio, Konomi, Fujiwara, Daisuke, Yamamoto, Norio

Journal:

Journal of Functional Foods

Year:

2017

Language:

english

File:

PDF, 651 KB

english, 2017

38

Administration of Lactococcus lactis strain Plasma induces maturation of plasmacytoid dendritic cells and protection from rotavirus infection in suckling mice

Jounai, Kenta, Sugimura, Tetsu, Morita, Yuji, Ohshio, Konomi, Fujiwara, Daisuke

Journal:

International Immunopharmacology

Year:

2018

Language:

english

File:

PDF, 891 KB

english, 2018

39

10.1271/kagakutoseibutsu.53.626

FUJIWARA, Daisuke, JOUNAI, Kenta, SUGIMURA, Tetsu

Year:

2015

File:

PDF, 1.82 MB

2015

40

The Chemotherapeutic Agent DMXAA as a Unique IRF3-Dependent Type-2 Vaccine Adjuvant

Tang, Choon Kit, Aoshi, Taiki, Jounai, Nao, Ito, Junichi, Ohata, Keiichi, Kobiyama, Kouji, Dessailly, Benoit H., Kuroda, Etsushi, Akira, Shizuo, Mizuguchi, Kenji, Coban, Cevayir, Ishii, Ken J., Ooi, E

Journal:

Year:

2013

Language:

english

File:

PDF, 657 KB

english, 2013

41

Oral Administration of Lactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection

Jounai, Kenta, Sugimura, Tetsu, Ohshio, Konomi, Fujiwara, Daisuke, Tregoning, John S

Journal:

Year:

2015

Language:

english

File:

PDF, 9.17 MB

english, 2015

42

Recognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccination

Jounai, Nao, Kobiyama, Kouji, Takeshita, Fumihiko, Ishii, Ken J.

Journal:

Frontiers in Cellular and Infection Microbiology

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

43

Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage

Kobiyama, Kouji, Kawashima, Akira, Jounai, Nao, Takeshita, Fumihiko, Ishii, Ken J., Ito, Tetsuhide, Suzuki, Koichi

Journal:

Frontiers in Genetics

Year:

2013

Language:

english

File:

PDF, 877 KB

english, 2013

44

Effect of Heat-Killed Lactobacillus paracasei KW3110 Ingestion on Ocular Disorders Caused by Visual Display Terminal (VDT) Loads: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Study

Morita, Yuji, Jounai, Kenta, Miyake, Mika, Inaba, Masaharu, Kanauchi, Osamu

Journal:

Year:

2018

Language:

english

File:

PDF, 541 KB

english, 2018

45

Lactobacillus paracasei KW3110 Prevents Blue Light-Induced Inflammation and Degeneration in the Retina

Morita, Yuji, Miwa, Yukihiro, Jounai, Kenta, Fujiwara, Daisuke, Kurihara, Toshihide, Kanauchi, Osamu

Journal:

Year:

2018

Language:

english

File:

PDF, 1.71 MB

english, 2018

46

A NOVEL FOOD CONSTITUENT POTENTIALLY MITIGATES INFLAMMATION IN PHYSIOLOGICALLY AGED MICE

Maruyama, M., Jounai, K., Sakamoto, A., Morita, Y., Kirisako, T., Matsuda, T., Fujiwara, D.

Journal:

Innovation in Aging

Year:

2017

Language:

english

File:

PDF, 112 KB

english, 2017

47

Plasmacytoid dendritic cell dysfunction caused by heat stress is improved by administration of Lactococcus lactis strain plasma in mice

Sugimura, Tetsu, Jounai, Kenta, Ohshio, Konomi, Fujiwara, Daisuke

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2019

Language:

english

File:

PDF, 968 KB

english, 2019

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